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Rybelsus

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FDA Approved Drugs
30 pills
1 month (3mg starting dose) ($1199.99)
$1199.99 Including Rx and delivery
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Weight loss

The power of Semaglutide - no
injection needed.
Now available as a tablet.

  • GLP-1 treatment: Semaglutide
  • Reduces your appetite
  • You feel fuller for longer
  • Daily tablet
  • Available in 3mg, 7mg and 14mg

How much weight will you lose?

What is your current weight?
lbs
What is your current height?

How to take

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Take 1 pill daily

Take Rybelsus as soon as you wake up.

Take the tablets on an empty stomach. Wait for at least 30 minutes before eating, drinking, or taking other oral tablets.

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Dose up

You will start on 3 mg for 30 days. Following this, you may be prescribed 7 mg for an additional 30 days.

Your dosage may be increased to the maximum of 14 mg.

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Missed a dose

If you miss a dose, skip it and continue with the regular schedule.

Do not take a double dose to make up for the missed dose.

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Rybelsus overview

Type of medicineGLP-1 receptor agonist
Used forTo treat type 2 diabetes and aid in weight loss
Active ingredient(s)Semaglutide
Works byMimicking a hormone that regulates blood sugar and appetite
Effective within4-6 weeks
Available asTablets
Available strength3mg, 7mg, 14mg
UsageOnce daily, taken orally
PackagingA box containing 30 tablets
ManufacturerNovo Nordisk
Is a generic available?No, Rybelsus is a brand name medication
StorageStore at room temperature, away from moisture and light
Prescription requiredYes, get it with our FREE online consultation
Who can consultAdults over 18 with type 2 diabetes or seeking weight loss

Note: Our medical team must review your online consultation before approving this treatment. They will determine if the requested treatment and quantity are safe, appropriate, and effective for you.

About Rybelsus

What is Rybelsus used for?

Rybelsus is a medication that helps manage type 2 diabetes. However, it is also effective when it comes to weight loss. It comes in a tablet form. Users only need to take it once a day.

When you have type 2 diabetes, your body finds it difficult to control your blood sugar levels. Rybelsus helps manage these levels and also helps reduce hunger, which can lead to eating less and usually results in weight loss.

Key benefits:

  • Rybelsus helps your body manage your blood sugar levels more effectively.
  • Many people may experience weight loss while taking Rybelsus, even if that’s not the main reason for their treatment.
  • When you take Rybelsus, you might feel less hungry throughout the day.
  • While many diabetes medications require injections, Rybelsus is conveniently taken orally just once a day, making it simpler to take.
  • Some studies suggest that it might help minimize heart-related risks in type 2 diabetics.

How does Rybelsus work?

The active ingredient in Rybelsus, semaglutide, mimics the GLP-1 (glucagon-like peptide-1) hormone in your body. This hormone does a few important things:

Releases insulin

GLP-1 hormone signals the pancreas to release insulin when blood sugar is high. It helps move sugar into cells for energy.

Slows digestion

The hormone slows down the movement of food through your stomach. This makes you feel full for longer after eating.

Reduces sugar production in the liver

The hormone decreases the amount of sugar a liver produces when it is not required.

Controls appetite

GLP-1 affects the areas of the brain that control appetite. As a result, you feel less hungry.


To summarize, Rybelsus mimics GLP-1, which controls your blood sugar levels. This causes weight loss by reducing your appetite.

How effective is it?

Rybelsus is effective in managing blood sugar in patients with type 2 diabetes and supporting weight loss.

A 6-month study was conducted with 703 type 2 diabetic patients. Researchers examined the effects of oral semaglutide on blood sugar levels and weight. The patients had an average starting HbA1c level of 8.0%, indicating poor blood sugar control.

Patients taking oral semaglutide experienced significant reductions in HbA1c compared to those taking the placebo. The reductions were as follows:

  • 7 mg dose: -1.2%
  • 14 mg dose: -1.4%

In the same 6-month study, the patients taking oral semaglutide experienced significant weight loss compared to those taking the placebo. The reductions were:

  • 7 mg dose: 5 pounds
  • 14 mg dose: 8 pounds
The effects of Rybelsus on type 2 diabetes & weight loss

One study has suggested that Rybelsus might help reduce the risk of heart problems in type 2 diabetics. More research is needed to confirm this.

Everyone responds differently to Rybelsus, so your experience may vary. Keep in mind that Rybelsus is most effective when combined with a healthy diet and regular exercise.

How long does it take to work?

Rybelsus starts working in your body immediately. However, it may take a few weeks before you notice the effects.

  • Your blood sugar levels may improve within the first few weeks of taking Rybelsus. However, it can take up to 4-6 weeks to get your blood sugar levels under control.
  • Weight loss with Rybelsus is gradual. You might start losing weight 4-6 weeks after starting the medication.

Remember, everyone responds differently to medication. Some people might notice the effects sooner. For others, it might take longer. It's important to keep taking Rybelsus as prescribed. Even if you don't notice immediate changes. We will check your progress after a few months to see how well it's working for you.

How to use Rybelsus

How and when to take Rybelsus

Dosage

You will first be prescribed 3 mg, which is the starting dose for Rybelsus. You will take 3 mg once daily for 30 days. Following this, you may be prescribed 7 mg to be taken daily for an additional 30 days.

Your dosage may be increased to 14 mg once daily if you need additional blood glucose control, after being on the 7 mg dose for at least 30 days.

However, your dosage may increase or stay constant depending on how well your body tolerates the medication.

Refer to the infographic below to understand Rybelsus dosage schedule.

Rybelsus dosage schedule

Day 1-30

3 mg

  • Once daily for 30 days
Day 31 -60

7 mg

  • Once daily for at least 30 days

Remember to get your 7 mg dosage before day 30

Day 61+

14 mg

  • Once daily if more weight loss is needed

Your doctor will assess if you need a higher dose after day 60

How do I take it?

It is important to take Rybelsus correctly. To do so, follow this step-by-step guide:

Key instructions

  • Take Rybelsus as soon as you wake up.
  • Take the tablets on an empty stomach. Wait for at least 30 minutes before eating, drinking, or taking other oral tablets.
  • Swallow the tablets whole with half a cup of water. Do not crush or chew the tablets.
  • If you miss a dose, skip it and continue with the regular schedule. Do not take a double dose to make up for the missed dose.

Pro tip

If you forget to take your medicines on time, set an alarm reminder to avoid missing your Rybelsus dose.

How long do I need to take Rybelsus for?

If Rybelsus works well for your glucose levels and there are no significant side effects, you may continue taking it indefinitely.

If you're taking Rybelsus for weight loss, the treatment duration might differ.

Your doctor will determine how long you should continue taking it, depending on your weight loss goals and current health status.

Even if you're feeling better, it's important to keep taking it as prescribed unless your doctor tells you otherwise.

What lifestyle changes should I make when taking Rybelsus?

These lifestyle changes can help enhance Rybelsus' effectiveness and improve your overall health.

Eat healthy

Focus on a balanced diet. Eat foods rich in lean protein, vitamins, and calcium. Limit processed foods, sugary drinks, and too many carbohydrates.

Exercise regularly

Try to exercise for at least 150 minutes every week for example, taking a brisk walk, jogging in the park, or going for a swim.

Stay hydrated

Drink plenty of water throughout the day. Hydration is important to manage the side effects caused by Rybelsus.

Monitor your blood sugar

If you have diabetes, regularly track your blood sugar levels.

Prioritize sleep

Aim for 7-8 hours of sleep each night to regulate hunger hormones and reduce cravings, supporting your weight loss with Rybelsus. Good sleep also promotes overall well-being and may help minimize side effects.

Manage stress

Chronic stress increases cortisol, which can trigger overeating and fat storage. Managing stress with techniques like yoga or meditation helps keep you on track with your weight loss goals while supporting your overall health.


When taking Rybelsus, it's a great opportunity to reassess your relationship with food. Focus on eating mindfully and choosing nutrient-dense foods. This doesn't mean restrictive dieting, but rather making sustainable, healthy choices that nourish your body. Remember, small, consistent changes often lead to the most significant long-term results.

Dr. Adrian Rawlinson Supervising Physician

How should I store this medicine?

Proper Rybelsus storage is important to maintain its effectiveness. Here are some guidelines:

Store Rybelsus at room temperature, between 68°F to 77°F. Keep the medication in its original packaging. Do not expose it to direct sunlight and heat. Keep out of reach of children and pets.

Pro tip

Storing Rybelsus while traveling

Planning a small trip? Keep Rybelsus in its original container and carry it in your carry-on luggage if you're flying.

Safety & side effects

Who can and cannot take Rybelsus?

Who can take Rybelsus

Rybelsus can be prescribed to:

  • Patients aged 18 years or older
  • Type 2 diabetics
  • Overweight or obese adults with a BMI of:
    • 30 kg/m2
    • 27 kg/m2 if one or more weight-related complications are present

Who may not be able to take Rybelsus

Rybelsus isn't suitable for everyone. You may not be able to take it if you:

  • Have type 1 diabetes
  • Are allergic to semaglutide or any of the ingredients in Rybelsus
  • Have Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2)
  • Have Medullary Thyroid Carcinoma (MTC), which is a type of thyroid cancer
  • Are pregnant or breastfeeding
  • Have severe kidney problems or are on dialysis
  • Have a history of pancreatitis
  • Have severe stomach or intestine problems, including delayed stomach emptying
  • Are under 18 years old

Tell your doctor about all your medical conditions and any medications you are taking. This will help them determine if Rybelsus is safe and appropriate for you.

What are Rybelsus side effects?

Rybelsus can cause side effects. Here are some of them:

Common side effects:

  • Nausea
  • Diarrhea
  • Vomiting
  • Stomach pain
  • Constipation
  • Headache
  • Fatigue
  • Decreased appetite

Common side effects such as nausea, vomiting and diarrhea are most common when first starting Rybelsus, and when increasing the dose.

“Following some general nausea tips may be helpful for you if you experience the gastrointestinal side effects mentioned above. These include:

  • Eat bland, low-fat foods, like crackers, toast, and rice
  • Eat foods that contain water, like soups and gelatin
  • Avoid fried, greasy, or sweet foods
  • Avoid lying down after you eat
  • Go outdoors for fresh air
  • Slowly eat smaller, more frequent meals
  • Drink clear or ice-cold drinks

If symptoms continue, consult your healthcare provider to discuss adjusting your dose or switching medications.

Dr. Adrian Rawlinson Supervising Physician

Less common side effects:

  • Dizziness
  • Gas
  • Stomach flu
  • Heartburn
  • Belching
  • Hair loss
  • Rare but serious side effects:
  • Inflammation of the pancreas (pancreatitis)
  • Changes in vision
  • Low blood sugar (hypoglycemia), especially if you're also taking other diabetes medications
  • Kidney problems
  • Allergic reactions

If you experience any of these side effects, contact us right away. For more information, please refer to the patient information leaflet.

Does Rybelsus interact with other medications?

Rybelsus can interact with other medications. This may affect its effectiveness or increase the risk of side effects. Be aware of the following interactions:

  • It may increase the risk of low blood sugar when taken with insulin or sulfonylureas. Examples include glipizide or glyburide.
  • Rybelsus affects how quickly your body absorbs other oral medications. To avoid this, take Rybelsus at least 30 minutes before other oral medications.
  • Rybelsus may increase the blood-thinning effects of Warfarin.
  • The medicine may reduce the effectiveness of oral contraceptives.
  • Rybelsus may affect thyroid hormone levels. So, check with your doctor about any dosage adjustments you may need.

This list is not complete. Other drugs, vitamins, and herbal products may interact with Rybelsus. To view the full list, visit Drugs.com.

What safety advice should be followed when taking Rybelsus?

When taking Rybelsus, it's important to follow certain safety guidelines. This ensures the medication works effectively and minimizes potential risks. Here's some key safety advice:

Category Safety Advice
Alcohol Use with caution Alcohol doesn't directly interact with Rybelsus. But, it can affect your blood sugar levels. Drink alcohol in moderation and monitor your blood sugar closely.
Pregnancy Consult us Rybelsus is not recommended during pregnancy. If you're pregnant or planning to become pregnant, make sure to include this information in your online consultation form.
Breastfeeding Consult us It's not known if Rybelsus passes into breast milk. Make sure you include this information in your online consultation form.
Driving Use with caution Rybelsus doesn't typically cause drowsiness. But if you experience dizziness or low blood sugar, avoid driving until you feel better.
Hydration Important Stay well-hydrated while taking Rybelsus, especially if you experience diarrhea or vomiting. This will help prevent dehydration.

Rybelsus and alternatives

Is Ozempic the same as Rybelsus?

Ozempic and Rybelsus are similar in what they do, but they are not the same. Both medications carry the same active ingredient, semaglutide. They are also both manufactured by Novo Nordisk.

Rybelsus is an oral tablet that needs to be taken every day. Whereas, Ozempic is an injection that you have to take once a week.

Both medicines are approved for managing type 2 diabetes. Ozempic has additional FDA approval for reducing major heart issue risks in type 2 diabetics.

What are some Rybelsus alternatives?

While Rybelsus can help manage type 2 diabetes and weight loss, it's not the only option available. Here's a comparison of some alternatives:

Medication Type Administration Frequency Main use Weight loss effect
Rybelsus (semaglutide) GLP-1 receptor agonist Oral tablet Daily Type 2 diabetes, weight loss Significant
Ozempic (semaglutide) GLP-1 receptor agonist Injection Weekly Type 2 diabetes, weight loss Significant
Metformin Biguanide Oral tablet Daily (1-3 times) Type 2 diabetes Modest
Victoza (liraglutide) GLP-1 receptor agonist Injection Daily Type 2 diabetes, weight loss Moderate
Trulicity (dulaglutide) GLP-1 receptor agonist Injection Weekly Type 2 diabetes Moderate
Jardiance (empagliflozin) SGLT2 inhibitor Oral tablet Daily Type 2 diabetes Modest

What makes Rybelsus better than alternatives?

Rybelsus stands out for several reasons:

  • It's the only oral GLP-1 medicine, offering benefits similar to injections.
  • It is highly effective for both blood sugar control and weight loss.
  • The once-a-day dose is convenient for many patients.
  • It may have additional benefits for heart health in type 2 diabetics.

However, the best treatment depends on individual factors. So it's important to discuss all options with your doctor.

Buying Rybelsus

Can I buy Rybelsus over the counter?

No, Rybelsus is not available to buy over the counter, it is a prescription-only medication. This means you require a prescription from a licensed doctor to buy the medicine.

This ensures that a medical professional evaluates your health condition to determine if Rybelsus is suitable for you to take.

At SpeedyHealth, you can get a prescription for Rybelsus by completing our online consultation. This process allows you to complete a consultation from your own home, without visiting your physician’s office.

How do I buy Rybelsus online from SpeedyHealth?

You can buy Rybelsus online through SpeedyHealth simply, safely, and securely. Just follow these steps:

  • Complete a short medical questionnaire
  • Our doctors will review your information to see if the medication is ideal for you.
  • We will issue a prescription if the doctor approves it.
  • Get free, discreet doorstep delivery with the tracking information provided.

Remember, if you have any questions during this process, our customer service team is available to assist you.

Why choose SpeedyHealth for your treatment?

SpeedyHealth offers comprehensive, convenient, and cost-effective healthcare for all. Here’s why so many patients trust us:

  • Free, discreet, doorstep delivery
  • Affordable cost
  • Secure data protection
  • Dedicated customer support

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