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Medically reviewed by Dr. Adrian Rawlinson
Written by our editorial team Last reviewed 30 January 2025
Type of medicine | Antibiotic |
Used for | Bacterial vaginosis |
Active ingredient(s) | Clindamycin phosphate |
Works by | Stopping bacteria from making the proteins they need to grow and multiply. |
Effective within | 3 to 7 days |
Available as | Vaginal cream |
Available strength(s) | 2% |
Usage | One applicatorful of vaginal cream (5 grams) is to be applied inside the vagina, preferably at bedtime, for either 3 or 7 consecutive days. |
Storage | Store the cream at room temperature between 68°F to 77°F |
Prescription required? | Yes, get it FREE with our online consultation. |
Who is suitable for an online consultation?** | Adult women suffering from bacterial vaginosis |
*Note: Our medical team must review your online consultation before approving this treatment. They will determine if the requested treatment and quantity are safe, appropriate, and effective for you.
Clindamycin vaginal cream is used to treat vaginal infections, such as bacterial vaginosis (BV). Symptoms of BV include unusual discharge, a fishy odor, and vaginal discomfort. Clindamycin works by stopping the growth of bacteria.
Clindamycin vaginal cream is approved by the FDA. At SpeedyHealth, our doctors are able to prescribe this medicine after you complete an online consultation for BV.
Clindamycin phosphate, the active ingredient in this vaginal cream, works by stopping bacteria from making the proteins they need to grow and multiply. It does this by attaching to a specific part of the ribosome, the cell's protein-making machinery.
Clindamycin mainly slows the growth of bacteria rather than killing them.
There are many benefits of using Clindamycin cream to treat BV:
Localised application
Since the cream is applied directly into the vagina, it acts locally, which minimizes the risk of side effects compared to oral antibiotics.
Convenient dosing
This medicine is applied once daily at bedtime, making it easy for patients to incorporate it into their daily routine.
Safe for patients
This vaginal cream is generally well-tolerated and is a good option for people who can’t take oral antibiotics.
Less chance of interactions
As a topical cream, there is a lower risk of Clindamycin interactions.
Clindamycin vaginal cream is effective in treating infections like bacterial vaginosis.
In a clinical trial of 134 patients, 65 patients were allocated to receive treatment with 5g of Clindamycin 2% vaginal cream and 69 patients received a placebo cream.
At the follow-up evaluation, the results showed that 77% of patients who received Clindamycin experienced complete cure or improvement of BV symptoms compared to only 25% of patients who received the placebo.
This cream is an effective option for many women; however, it may not be suitable for everyone.
Clindamycin vaginal cream is suitable for adult women suffering from bacterial vaginosis who prefer using a localised vaginal treatment.
Do not use this cream if you are allergic to Clindamycin, Lincomycin or any of the other ingredients of this medicine. You should also avoid this medicine if you have a history of inflammatory bowel disease or colitis linked to taking antibiotics.
Speak to your doctor before taking this medicine if you:
To treat BV, the recommended dose is one applicatorful (5 grams) of cream applied inside the vagina once daily, at bedtime, for either 3 or 7 consecutive nights. Using this medicine at bedtime reduces the chance of it leaking out during the day.
Here’s how to use Clindamycin vaginal cream: | |
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If you forget a dose and are just a few hours late, use it right away. However, if it is nearly time for your next application, skip the missed dose and apply your next dose at your usual time. Do not use a double dose to make up for a missed dose.
This medicine starts working as soon as you use the first dose. The peak concentration of the medication is reached approximately 10 hours after the dose. You should notice your symptoms improving within a few days of using this medicine and complete resolution within 7 days. However, if your infection worsens or symptoms don’t resolve, speak to your doctor.
Use this cream for 3 or 7 days in a row, depending on your doctor's instructions. Make sure to finish the entire treatment, even if you start feeling better before it’s done. If you stop early, the infection might not go away completely or could come back.
It’s important to make certain lifestyle changes to ensure this medicine is effective:
Use effective contraception
Clindamycin vaginal cream contains a mineral oil which can weaken latex or rubber products such as condoms or diaphragms. Do not rely on condoms or contraceptive diaphragms when using this medicine and for 72 hours following treatment. Speak to your doctor about alternative contraceptives.
Avoid sexual activity
Avoid sexual intercourse while using this medicine, as the cream may reduce the effectiveness of some contraceptives, and sexual activity can irritate the area or interfere with healing.
Maintain good hygiene
Make sure to wash your genital area gently with mild soap and water. Avoid using scented soaps, wipes, or sprays, as these can disrupt your natural vaginal flora.
Wear breathable underwear
Wear cotton underwear or other breathable fabrics to help keep the vaginal area dry. Avoid tight-fitting underwear as this can trap moisture.
Avoid douching
Avoid douching, as this can disturb the normal vaginal balance and hinder the treatment progress.
Like many medicines, Clindamycin can also cause some side effects, although not everyone experiences them.
Some common clindamycin vaginal cream side effects that could affect up to 1 in 10 people include:
Some uncommon side effects that may affect up to 1 in 100 people include:
If you get any side effects, talk to your doctor. This includes any possible side effects not listed here. For a full list of side effects, consult the patient information leaflet.
This medicine can interact with other prescription medicines, over-the-counter drugs, vitamins, and natural products. Tell your doctor about all other medicines you use.
Clindamycin may increase the effects of drugs used during surgery that help relax muscles. Tell your healthcare professional that you are using Clindamycin if you are due to have any medical procedures.
Avoid using Clindamycin together with Erythromycin, as they can counteract each other's effects.
Do not use any other vaginal products without informing a healthcare professional.
This is not a complete list of interactions. For a full list of drug interactions, visit drugs.com.
The safety information to follow when taking this medicine can be found in the table below:
Category | Safety | Advice |
---|---|---|
Alcohol | Safe | This medicine does not directly interact with alcohol. |
Pregnancy | Consult your doctor | If you are pregnant or planning to become pregnant, consult your doctor before using this medicine. |
Breastfeeding | Consult your doctor | This medicine may pass into breast milk. Speak to your healthcare provider if you plan to breastfeed. |
Driving | Safe | This medicine doesn’t affect your ability to drive. |
Store this cream at a controlled room temperature 68° to 77°F and do not freeze. Avoid heat over 86°F as well as high humidity. Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date stated on the tube. Do not throw away any unused or expired medicines via wastewater or household waste. Take them to a pharmacy to dispose of safely. This will help to protect the environment.
No, you cannot buy this medicine over the counter. You need a prescription from a doctor to purchase this medicine. This is so that a doctor can determine if this cream is suitable for you.
If you require a prescription, fill out our online consultation form; it is a quick and easy process. If one of our doctors approves of your prescription, you will receive it electronically.
Yes, you can buy Clindamycin vaginal cream online from SpeedyHealth. All you have to do is:
Your privacy is our top priority. SpeedyHealth uses secure, encrypted transactions and complies with USA medical standards to maintain confidentiality.
Here’s why you should choose SpeedyHealth to manage your medicines easily:
The price of Clindamycin vaginal cream at SpeedyHealth includes everything you need:
At SpeedyHealth, this gel starts at -
Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.
If this medicine is not right for you, there are other options for treating BV. These include Metronidazole vaginal gel or Tinidazole tablets.
Feature | Metronidazole | Clindamycin | Tinidazole |
---|---|---|---|
Route | Gel (intravaginal) or Tablets (oral) | Cream (intravaginal) | Tablets (oral) |
Treatment duration |
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3 or 7 days | 5 days |
Usage |
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Apply 5g at bedtime | Take 1g once daily with food |
Effectiveness | 77% cure rate | 91% cure rate | |
Best for | Patients needing flexible options (oral or vaginal) | Patients preferring local treatment with fewer doses | Patients seeking simple, once-daily oral medication |
Pricing from | $39.99 | - | - |