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Used For Accupril (Quinapril Hydrochloride) is generally prescribed for the treatment of hypertension (increase in blood pressure). It can be used on its own or as a supplement with thiazide diuretics. Accupril may also be prescribed as adjunctive therapy to the conventional therapies used in the management of heart failure and can be used with diuretics and / or digitalis.
Directions For patients not on diuretics, the recommended starting dosage of Accupril is one tablet of 10 or 20 mg once a day. For patients above the age of 65, 10 mg Accupril tablet once daily followed by titration to the recommended dosage should be followed.
How It Works Accupril works by inhibiting the renin-angiotensin-aldosterone system of the body. This might result in changes in the renal function of certain patients. For patients with severe heart failure issues, Accupril may result in oliguria and / or progressive azotemia and in extremely rare cases - acute renal failure and / or death. Accupril should not be administered to pregnant patients as this can cause damage to the foetus.
Side Effects Accupril can disrupt the renal function in susceptible individuals. It can also commonly lead to back pain, malaise, viral infections, flatulence, dry mouth or throat, constipation, abnormal liver function tests and dyspepsia. If a pregnant woman is administered Accupril, it can cause fetal and neonatal morbidity as well as death of the unborn baby.
Other Info Accupril can be split and taken at half the dose but should only be done after medical advice.
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