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Used For Amitriptyline is in a class of drugs called tricyclic antidepressants. Amitriptyline is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide. Amitriptyline is also sometimes used to treat certain types of pain.
Directions Take amitriptyline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass (8 oz) of water. Amitriptyline may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions.
How It Works Amitriptyline affects chemicals in the brain that may become unbalanced and cause depression.
Side Effects If you experience any of the following serious side effects, stop taking amitriptyline and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision, headache); difficulty urinating; or fever with increased sweating, muscle stiffness, or severe muscle weakness.
Other Info Do not stop taking amitriptyline suddenly. This could cause symptoms such as nausea, headache, and malaise.
It may be 4 weeks or more before you start to feel better, but do not stop taking amitriptyline without first talking to your doctor.
Store amitriptyline at room temperature away from moisture and heat.
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